How does PRP work

Platelet rich plasma (PRP) is my FAVORITE procedure for anti-aging and I LOVE what it can do to heal joints and tendons. Did you know PRP can also treat scars?? Yep, scars from surgery, acne, or injury!

How do platelets work for anti-aging, tissue and wound repair?

Platelets contain 30 different bioactive proteins which play a role in hemostasis and tissue healing. There are seven fundamental protein growth factors that platelets contain that initiate wound healing and tissue regeneration (Dhurat, R.):

1. Platelet derived growth factor - regulates collagen synthesis, stimulates fibroblasts/glial and smooth muscle cells

2. Transforming growth factor - stimulates mesenchymal cell proliferation

3. Vascular endothelial growth factor - increases angiogenesis, stimulates endothelial cells

4. Epidermal growth factor - Stimulates mesenchymal/endothelial mitogenesis

5. Fibroblast growth factor -stimulates mesenchymal cells and promotes growth

6. Connective tissue growth factor - promotes angiogenesis and cartilage formation

7. Insulin like growth factor - stimulates fibroblasts and protein synthesis

(Sunith, R.V.)

The process matters...

Not all PRP is created equal. There are many PRP systems on the market that facilitate the preparation of PRP for use in aesthetics and orthopedics. So what makes a good PRP system?

• The concentration of platelets obtained

• Centrifugal force

• Draw of blood

• Time

• Collection tube

• Temperature

• Anticoagulant

• Activation

(Dhurat, R.)